SrasV1, 2020, Analysis, bibRecord, 000644

False-Negative Results of Real-Time Reverse-Transcriptase Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2: Role of Deep-Learning-Based CT Diagnosis and Insights from Two Cases

Identifieur interne : 000644 ( 2020/Analysis ); précédent : 000643; suivant : 000645

False-Negative Results of Real-Time Reverse-Transcriptase Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2: Role of Deep-Learning-Based CT Diagnosis and Insights from Two Cases

Auteurs : Dasheng Li [République populaire de Chine] ; Dawei Wang [République populaire de Chine] ; Jianping Dong [République populaire de Chine] ; Nana Wang [République populaire de Chine] ; He Huang [République populaire de Chine] ; Haiwang Xu [République populaire de Chine] ; Chen Xia [République populaire de Chine]

Source :

Korean Journal of Radiology [ 1229-6929 ] ; 2020.

RBID : PMC:7082661

Descripteurs français

KwdFr :
- Adulte, Faux négatifs, Humains, Infections à coronavirus (diagnostic), Infections à coronavirus (imagerie diagnostique), Infections à coronavirus (virologie), Mâle, Nourrisson, Pneumopathie virale (imagerie diagnostique), Pneumopathie virale (virologie), RT-PCR, Techniques de laboratoire clinique, Tomodensitométrie.
MESH :
- diagnostic : Infections à coronavirus.
- imagerie diagnostique : Infections à coronavirus, Pneumopathie virale.
- virologie : Infections à coronavirus, Pneumopathie virale.
- Adulte, Faux négatifs, Humains, Mâle, Nourrisson, RT-PCR, Techniques de laboratoire clinique, Tomodensitométrie.

English descriptors

KwdEn :
- Adult, Betacoronavirus (genetics), Betacoronavirus (isolation & purification), Clinical Laboratory Techniques, Coronavirus Infections (diagnosis), Coronavirus Infections (diagnostic imaging), Coronavirus Infections (virology), Deep Learning, False Negative Reactions, Humans, Infant, Male, Pneumonia, Viral (diagnostic imaging), Pneumonia, Viral (virology), Reverse Transcriptase Polymerase Chain Reaction, Tomography, X-Ray Computed.
MESH :
- diagnosis : Coronavirus Infections.
- diagnostic imaging : Coronavirus Infections, Pneumonia, Viral.
- genetics : Betacoronavirus.
- isolation & purification : Betacoronavirus.
- virology : Coronavirus Infections, Pneumonia, Viral.
- Adult, Clinical Laboratory Techniques, Deep Learning, False Negative Reactions, Humans, Infant, Male, Reverse Transcriptase Polymerase Chain Reaction, Tomography, X-Ray Computed.

Abstract

The epidemic of 2019 novel coronavirus, later named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still gradually spreading worldwide. The nucleic acid test or genetic sequencing serves as the gold standard method for confirmation of infection, yet several recent studies have reported false-negative results of real-time reverse-transcriptase polymerase chain reaction (rRT-PCR). Here, we report two representative false-negative cases and discuss the supplementary role of clinical data with rRT-PCR, including laboratory examination results and computed tomography features. Coinfection with SARS-COV-2 and other viruses has been discussed as well.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082661

DOI: 10.3348/kjr.2020.0146
PubMed: 32174053
PubMed Central: 7082661

Affiliations:

République populaire de Chine

Links to Exploration step

PMC:7082661

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p>The epidemic of 2019 novel coronavirus, later named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still gradually spreading worldwide. The nucleic acid test or genetic sequencing serves as the gold standard method for confirmation of infection, yet several recent studies have reported false-negative results of real-time reverse-transcriptase polymerase chain reaction (rRT-PCR). Here, we report two representative false-negative cases and discuss the supplementary role of clinical data with rRT-PCR, including laboratory examination results and computed tomography features. Coinfection with SARS-COV-2 and other viruses has been discussed as well.</p>
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</author>
<author><name sortKey="Baric, Rs" uniqKey="Baric R">RS Baric</name>
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<author><name sortKey="De Groot, Rj" uniqKey="De Groot R">RJ de Groot</name>
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<author><name sortKey="Drosten, C" uniqKey="Drosten C">C Drosten</name>
</author>
<author><name sortKey="Gulyaeva, Aa" uniqKey="Gulyaeva A">AA Gulyaeva</name>
</author>
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<author><name sortKey="Zhao, W" uniqKey="Zhao W">W Zhao</name>
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<author><name sortKey="Zheng, C" uniqKey="Zheng C">C Zheng</name>
</author>
<author><name sortKey="Wang, F" uniqKey="Wang F">F Wang</name>
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<author><name sortKey="Mei, X" uniqKey="Mei X">X Mei</name>
</author>
<author><name sortKey="Zhang, N" uniqKey="Zhang N">N Zhang</name>
</author>
<author><name sortKey="Huang, M" uniqKey="Huang M">M Huang</name>
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<author><name sortKey="Zeng, X" uniqKey="Zeng X">X Zeng</name>
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False-Negative Results of Real-Time Reverse-Transcriptase Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2: Role of Deep-Learning-Based CT Diagnosis and Insights from Two Cases

False-Negative Results of Real-Time Reverse-Transcriptase Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2: Role of Deep-Learning-Based CT Diagnosis and Insights from Two Cases

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

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